The invention relates to an injection molding machine. A fixed mold and a movable mold which are used for assembling a die are arranged on the machine table, and a guide column is utilized to string the fixed mold, the movable mold and an adjustable mold, so that a driving mechanism can push the movable mold to be moved and displaced on the guide column and to be further closed and opened; the guide column is respectively penetrated in the oblique diagonal positions of all the molds, and is used as the guide rail for pushing the movable mold to be closed in the oblique two-point form, so thatwhen the die is assembled and disassembled, a movable operation space for clamping and assembling the die is formed from the oblique diagonal positions to the horizontal side and the vertical side, so as to achieve the purpose of facilitating the disassembly and assembly operations; in addition, through the enlarged operation space, the operator can conveniently carry out inspection and maintenance during the injection process.